Lungeembolisme hos en pasient med Klinefelters syndrom

Studies of Different Clinical Manifestations of Sarcoidosis and the Role of Genetic Factors

Sarcoidosis is a systemic disease of unknown etiology characterized by the formation of non-necrotizing granulomas in the affected organs. Engagement of the lungs and/or thoracic lymph nodes (LN) are found in more than 90 % of all cases, but almost any organ such as the eyes, skin, heart and nervous system can be involved. Genetic factors influence the risk for disease as well as the clinical p...

Rachel Carson Syndrom

For years some ecologists have been convinced that pesticides are contributing to a decline in amphibian species around the globe. From an apparent epidemic of deformed frogs in Minnesota to the near disappearance of yellow-legged frogs from California’s Sierra Nevada Mountains, pesticides have been considered prime suspects. This suspicion is no doubt rooted in the belief by the ecological com...

Feline diabetes mellitus Aspects on epidemiology and pathogenesis

Diabetes mellitus (DM) är en endokrin sjukdom hos katt, som är slående lik typ 2 diabetes hos människa. Katter och människor delar många riskfaktorer för sjukdomen, inklusive ett samband med insulinresistens kopplat till övervikt och en stillasittande livsstil. Det finns också patofysiologiska likheter, med förlust av β-celler och inlagring av amyloid i Langerhans öar i bukspottkörteln. En rasp...

Das Hepatopulmonale Syndrom

MEN-2-Syndrom: Was gibt es Neues?

Multiple Endocrine Neoplasia Type 2 (MEN-2): An Update. Multiple endocrine neoplasia type 2 (MEN-2) is an autosomal dominant hereditary cancer syndrome. The disorder is caused by missense mutations of the RET proto-oncogene that result in their gain of function. Three distinct clinical subtypes of MEN-2 are characterized: MEN-2A, MEN-2B, and familial MTC (FMTC). The precise RET mutations may su...